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US 2019/0167803 A1Published application
Tlr9 targeted cytotoxic agents
OwnerAlan F. List, Sheng Weiinventors
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Abstract
Disclosed are compositions and methods for targeted treatment of TLR9-expressing cancers. In particular, molecules containing a TLR9 targeting ligand, such as a CpG oligodeoxynucleotide, that target cytotoxic agents to TLR9-expressing malignant cells are disclosed.
Claims13
A molecule comprising a toll like receptor-9 (TLR9) targeting ligand conjugated to a cytotoxic agent, wherein the cytotoxic agent is not a polynucleotide.
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Dependencies are inferred from the claim text.