Formulations for Nutritional Support in Subjects in Need Thereof

A formulation for oral administration comprising a protein component, wherein the protein component comprises:

• (a) one or more digestion-aiding proteins, selected from the group consisting of whey protein hydrolysate (WPH) protein, alpha-lactalbumin, and κ-casein;
• and
• (b) one or more immunoprotective proteins, selected from the group consisting of lactoferrin, osteopontin, κ-casein, haptocorrin, lysozyme, secretory IgA, and bile-salt stimulated lipase;
• wherein the one or more digestion-aiding proteins and the one or more immunoprotective proteins comprise about 5% to about 95% by weight of the protein component;
• and
• wherein the formulation further comprises a milk component comprising milk from a non-human source.

A formulation for oral administration comprising a protein component, a fat component, a carbohydrate component, and milk from a bovine source, wherein:

• (a) the protein component comprises whey protein hydrolysate (WPH) protein, alpha-lactalbumin, lactoferrin, and osteopontin, wherein the WPH protein comprises about 20% to about 50% by weight of the protein component, the alpha-lactalbumin comprises about 10% to about 20% by weight of the protein component, the lactoferrin comprises about 6% to about 9% by weight of the protein component, and the osteopontin comprises about 0.5% to about or about 1.5% by weight of the protein component;
• (b) the fat component comprises innate milk fat globule membrane, added milk fat globule membrane, phospholipids, non-hexane extracted docosahexaenoic acid, hexane extracted arachidonic acid, non-hexane extracted arachidonic acid, or a combination thereof;
• (c) the carbohydrate component comprises lactose and galactooligosaccharide;
• and
• (d) the whole milk is in an amount to provide about 15% or about 25% by weight of the protein component.