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US 2019/0167727 A1Published application
Neuroprotective composition, preparation process thereof and medical uses thereof
AssigneeCaire Medical-Biotechnology International Co.
InventorsTe-Fu CHEN, Kuo-Chuan WANG
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Abstract
The invention relates to a neuroprotective composition derived from mesenchymal stem cells, especially a neuroprotective composition derived from the primary culture of dental pulp mesenchymal stem cells. The invention also relates to a process for preparing the neuroprotective composition, as well as the medical use of the neuroprotective composition in the treatment of Parkinson's disease.
Claims4
A method for treating Parkinson's disease in a subject, comprising administering to said subject an effective amount of a neuroprotective composition to suppress neuronal damage;
- wherein the neuroprotective composition is obtainable by a process comprising the steps of:
- (i) culturing mesenchymal stem cells in a serum-free basal culture medium for at least 3 hours to obtain a cell culture;
- and
- (ii) processing the cell culture obtained in step (i) to obtain an aqueous fraction with a molecular weight of no more than about 5 kDa as the neuroprotective composition.
1 more element
Dependencies are inferred from the claim text.