Dosing Regimens for the Mobilization of Hematopoietic Stem Cells

A method of treating a stem cell disorder in a human patient, the method comprising infusing into the patient a therapeutically effective amount of hematopoietic stem cells or progeny thereof mobilized by a method comprising:

• administering to a human donor (i) Gro-β T at a dose of about 150 μg/kg, wherein the Gro-β T is administered intravenously to the donor and (ii) about 240 μg/kg plerixafor or a pharmaceutically acceptable salt thereof, wherein the plerixafor or pharmaceutically acceptable salt thereof is administered subcutaneously to the donor.

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