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US 2019/0167709 A1Published application
Compositions and methods for inducing apoptosis
AssigneeUniversity of Utah Research Foundation
InventorsJindrich Henry Kopecek, Jiyuan Yang, Te-Wei Chu
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Abstract
In an aspect, the invention relates to compositions, method, and kits for inducing apoptosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Claims39
A method of inducing apoptosis, the method comprising:
- (i) contacting a population of cells with a first complex comprising a targeting moiety and a morpholino;
- and
- (ii) contacting a population of cells with a second complex comprising a copolymer carrier and one or more morpholinos;
- wherein the contacting of the cells with the first complex and the second complex induces apoptosis of the cells.
1 more element
A method of inducing apoptosis, the method comprising:
- contacting a population of cells with a composition comprising a first complex comprising a targeting moiety and a morpholino and a second complex comprising a complex comprising a copolymer carrier and one or more morpholinos, wherein the contacting of the cells with the composition induces apoptosis of the cells.
A kit comprising (i) a first complex comprising a targeting moiety and a morpholino, and (ii) a second complex comprising a copolymer carrier and one or more morpholinos.
Dependencies are inferred from the claim text.