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US 2019/0167693 A1Published application
METHOD OF TREATING PATIENTS COADMINISTERED A FACTOR Xa INHIBITOR AND VERAPAMIL
AssigneeMorgandane Scientific, LLC
InventorsSundar SRINIVASAN, Maulik PATEL, Christina CHOW
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Abstract
The present disclosure in various embodiments teaches methods of treating patients in need of treatment with a Factor Xa inhibitor, and who are also concomitantly administered verapamil.
Claims10
A method of reducing the risk of cardiovascular death, myocardial infarction, and stroke in a patient in need of treatment with rivaroxaban and verapamil, comprising:
- (a) administering about 100 to about 480 mg verapamil daily to the patient;
- and
- (b) administering a daily dose of 2.5 mg to 4 mg of rivaroxaban to the patient;
- wherein the patient has a creatinine clearance (CLCr) of >50 mL/min to 79 mL/min.
1 more element
Dependencies are inferred from the claim text.