Back to results
US 2019/0167643 A1Published application
Formulations of deferasirox and methods of making the same
AssigneeDispersol Technologies, LLC
InventorsDave A. MILLER, Justin M. KEEN, Sandra U. KUCERA
Life of this patent
Estimating the term…
Abstract
The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
Claims26
A method of making a pharmaceutical composition comprising:
- (a) providing crystalline deferasirox (DFX) and one or more pharmaceutically acceptable excipients;
- (b) compounding the materials of step (a) in a thermokinetic mixer at less than or equal to 200° C. for less than about 300 seconds,
- wherein the thermokinetic compounding of DFX and the one or more pharmaceutically acceptable excipients forms a melt blended pharmaceutical composite.
26-138. (canceled)
Dependencies are inferred from the claim text.