Methods and compositions for reducing ocular discomfort
AssigneeBrien Holden Vision Institute Limited
InventorQian Garrett
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Abstract
The invention relates to compositions and devices which include an osmolytic agent, in particular a betaine or carnitine compound, for reducing ocular discomfort associated with various diseases or conditions, in particular diseases or conditions associated with high tear film tonicity. The invention also relates to methods of treating or preventing various diseases or conditions using compositions and devices of the invention.
Claims24
An ophthalmic device including a physiologically acceptable osmolytic agent, wherein the device permits a therapeutically effective amount of the agent to be desorbed from the device into the eye during wear.
Use of a betaine and/or a carnitine compound in the preparation of an medicament for inhibiting, reducing or ameliorating ocular discomfort associated with high tear film tonicity.
A solution for adding a therapeutically effective amount of one or more betaine compounds and/or one or more carnitine compounds to an ophthalmic device, the solution including a betaine and/or a carntine compound and a physiologically acceptable carrier, dliuent or excipient.
Dependencies are inferred from the claim text.