Use of histone acetyltransferase inhibitor amidoximes as anti-proliferative agents
AssigneeTexas Woman's University
InventorsMichael Bergel, James E. Johnson, Debra Dolliver, Sudheer Dhanireddy, Amon Gekombe
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Abstract
Described herein is the use of bisamidoximes compounds for the treatment of cancer. In preferred embodiments, combinations of two or more bisamidoximes or combinations of a bisamidoxime and another anti-cancer agent were found to be effective against various types of cancer cells.
Claims20
A method of treating cancer in a subject comprising administering to a subject who would benefit from such treatment a therapeutically effective amount of a pharmaceutical composition comprising one or more bisamidoximes.
A method of treating cancer in a subject comprising administering to a subject who would benefit from such treatment a therapeutically effective amount of a pharmaceutical composition comprising an anticancer agent and one or more bisamidoximes.
20-23. (canceled)
Dependencies are inferred from the claim text.