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US 2019/0167582 A1Published application
Methotrexate Composition
AssigneeRosemont Pharmaceuticals Ltd
InventorsCarl Tierney, Stacey Powell, Peter Braybrooke, Geraint Jones
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AssigneeRosemont Pharmaceuticals Ltd
InventorsCarl Tierney, Stacey Powell, Peter Braybrooke, Geraint Jones
Estimating the term…
A Methotrexate composition for oral administration is provided comprising a pharmaceutically acceptable salt of Methotrexate and an aqueous carrier agent. The Methotrexate salt is substantially or completely soluble in the aqueous carrier agent, forming an aqueous solution. There is also provided a method of manufacturing a Methotrexate composition for oral administration, comprising mixing a pharmaceutically acceptable salt of Methotrexate with an aqueous carrier agent until the Methotrexate salt is substantially or completely soluble in the carrier agent to form an aqueous solution.
A Methotrexate composition for oral administration, said composition comprising a pharmaceutically acceptable salt of Methotrexate, a citrate buffer system, a preserving agent, and purified water, wherein the pH of the composition is 6 to 7.
A Methotrexate composition for oral administration, said composition comprising a pharmaceutically acceptable salt of Methotrexate, a citrate buffer system, Sodium Methyl Hydroxybenzoate, Sodium Propyl Hydroxybenzoate, Sucralose, and purified water, wherein the pH of the composition is 6 to 7.
Dependencies are inferred from the claim text.