Itraconazole dry powders
AssigneePulmatrix Operating Company, Inc.
InventorsJason M. Perry, Jean C. Sung, David L. Hava
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AssigneePulmatrix Operating Company, Inc.
InventorsJason M. Perry, Jean C. Sung, David L. Hava
Estimating the term…
In one aspect, a dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 75%, sodium sulfate in an amount of about 10% to about 55%, and optionally one or more other excipients, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%. In another aspect, a dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 55%, sodium chloride in an amount of about 30% to about 40%, and leucine in an amount of about 10% to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.
A dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 75%, sodium sulfate in an amount of about 10% to about 55%, and optionally one or more other excipients, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.
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A dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 55%, sodium chloride in an amount of about 30% to about 40%, and leucine in an amount of about 10% to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.
A dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 50%, sodium chloride in an amount of about 35%, and leucine in an amount of about 15%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.
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Dependencies are inferred from the claim text.