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US 2019/0167567 A1Published application
Topical compositions and methods of using the same
AssigneeNovan, Inc.
InventorsRyan Doxey, Adam Sabouni, Eleftherios Kougoulos, Nathan Stasko
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Abstract
The present invention relates generally to compositions and methods of using the same.
Claims23
A method of treating acne vulgaris, the method comprising topically applying to the skin of a subject a composition comprising:
- a first viscosity increasing agent;
- at least one polyhydric alcohol;
- at least one buffering agent;
- a second viscosity increasing agent;
- at least one organic solvent;
- at least one humectant;
- at least one water repellent;
- at least one active pharmaceutical ingredient;
- and
- water.
7 more elements
A composition in the form of a hydrogel, the hydrogel having a pH of about 3 to about 8 and is compatible with a second composition to form a structure in which an active pharmaceutical ingredient is suspended, upon combination of the hydrogel and the second composition, the hydrogel comprising:
- at least one polyhydric alcohol;
- at least one viscosity increasing agent;
- at least one buffering agent;
- and
- water.
2 more elements
A method of treating acne vulgaris, the method comprising:
- providing an anhydrous topical gel comprising a nitric oxide-releasing active pharmaceutical ingredient;
- providing a hydrogel;
- combining the anhydrous topical gel comprising the nitric oxide-releasing active pharmaceutical ingredient and the hydrogel to provide a nitric oxide-releasing topical composition;
- and
- topically applying to the skin of a subject the nitric oxide-releasing topical composition.
2 more elements
Dependencies are inferred from the claim text.