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AssigneeUpm-Kymmene Corporation
InventorsMarjo Yliperttula, Arto Urtti, Yan-Ru Lou, Melina Malinen, Patrick Laurén, Liisa Kanninen, Johanna Niklander, Petter Somersalo, Riina Harjumäki
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The present invention relates a method for chemical testing, comprising culturing cells in a first plant-derived nanofibrillar cellulose (NFC) hydrogel to obtain in vivo like cells; exposing the in vivo like cells to a test chemical; optionally within another plant-derived NFC hydrogel; incubating the exposed in vivo like cells; detecting during or after incubating, the impact of the test chemical on the in vivo like cells by at least one detection; and removing the plant-derived NFC hydrogel at least once at any stage after obtaining the in vivo like cells and before at least one detection used for detecting the impact of the test chemical on the in vivo like cells. The invention further relates to the use of plant-derived NFC hydrogel in a method for chemical testing, the use of in vivo like cells obtained by culturing cells in plant-derived NFC hydrogel for chemical testing and to a kit for chemical testing comprising plant-derived NFC hydrogel, instructions and a cell or test chemical library.
A method for chemical testing, comprising
Use of plant-derived NFC hydrogel in a method for chemical testing, wherein a NFC hydrogel is used for culturing cells on or in said hydrogel to obtain in vivo like cells;
Use of in vivo like cells obtained by culturing cells on or in plant-derived NFC hydrogel for chemical testing, which use comprises removing the plant-derived NFC hydrogel before detecting the impact of a test chemical on the in vivo like cells.
Dependencies are inferred from the claim text.