Improved magnesium ion selective membranes
AssigneeSiemens Healthcare Diagnostics Inc.
InventorsJohn Benco, Robert Bergquist
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Abstract
The present invention is directed to membranes, sensors, systems and process for the detection of magnesium ions in protein-containing samples. The novel membranes, sensors, systems, and processes are based upon the discovery that the lipophilcity of the plasticizer (or blend of plasticizers) utilized in the formulation of magnesium ion selective membranes for clinical use is inversely proportional to the sensitivity of the plasticizer(s) and directly proportional to the use life thereof.
Claims18
A magnesium ion selective membrane comprising:
- a polymer material;
- a magnesium-selective material;
- and
- a plasticizer comprising a measured log P value of greater than about 5.8 and less than about 12.8.
A process for analyzing a protein-based sample for magnesium comprising:
- a sensor including a magnesium ion selective membrane that comprises:
- a polymer material;
- a magnesium-selective material;
- and
- a plasticizer comprising a measured log P value of greater than 5.8 and less than 12.8,
- introducing a protein-containing sample with the sensor;
- and
- determining a presence of magnesium in the sample after the contacting.
Dependencies are inferred from the claim text.