Novel metalloproteases
AssigneeDanisco US Inc.
InventorsLilia M. Babe, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
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Abstract
Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
Claims67
A polypeptide comprising an amino acid sequence having at least 60% sequence identity to an amino acid sequence selected from the group consisting of SEQ ID NO:
- 3, 6, 9 and 13.
The polypeptide of any of the above claims, wherein said amino acid sequence is the amino acid sequence selected from the group consisting of SEQ ID NO:
- 3, 6, 9 and 13.
The polypeptide of any of the above claims, wherein said polypeptide is derived from a member of the Actinomycetales.
The polypeptide of any of the above claims, wherein said polypeptide is derived from a member of the Streptomyces. spp.
The polypeptide of any of the above claims, wherein said polypeptide has protease activity.
The polypeptide of any of the above claims, wherein said polypeptide retains at least 50% of its maximal activity between pH 4.5 and 9.5.
The polypeptide of any of the above claims, wherein said polypeptide retains at least 50% of its maximal activity between 30° C. and 65° C.
The polypeptide of any of the above claims, wherein said polypeptide has cleaning activity in a detergent composition.
The polypeptide of any of the above claims, wherein said polypeptide is a recombinant polypeptide.
A composition comprising the polypeptide of any of the above claims.
A nucleic acid sequence comprising a nucleic acid sequence:
- (i) having at least 70% identity to SEQ ID NO:
- 4, 10 or 14;
- or
- (ii) being capable of hybridizing to a probe derived from the polynucleotide sequence set forth in SEQ ID NO:
- 4, 10 or 14 under conditions of intermediate to high stringency;
- or
- (iii) being complementary to the polynucleotide sequence set forth in SEQ ID NO:
- 4, 10 or 14.
Dependencies are inferred from the claim text.