Animal protein-free media for cultivation of cells
AssigneesBaxalta Incorported, Baxalta Incorporated
InventorsLeopold Grillberger, Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
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Abstract
The present invention relates to animal protein-free cell culture media comprising polyamines and a plant- and/or yeast-derived hydrolysate. The invention also relates to animal protein-free culturing processes, wherein cells can be cultivated, propagated and passaged without adding supplementary animal proteins in the culture medium. These processes are useful in cultivating cells, such as recombinant cells or cells infected with a virus, and for producing biological products by cell culture processes.
Claims15
An animal protein-free cell culture medium, comprising at least one polyamine and at least one protein hydrolysate derived from the group consisting of plants and yeast, wherein the polyamine is present in the culture medium in a concentration ranging from about 0.5 to about 30 mg/L.
Dependencies are inferred from the claim text.