US 2018/0022815 A1Published application

Bi-specific chimeric antigen receptor and uses thereof

AssigneeUniversity of Florida Research Foundation, Inc.

InventorLung-Ji CHANG

Life of this patent

Estimating the term…

Abstract

Provided herein are bi-specific chimeric antigen receptors (CARs), such as those specific for CD138 and BCMA. Use of the CARs in immune cells (e.g., T cells), compositions, and methods are also contemplated.

Claims27

Dependent claims

A chimeric antigen receptor (CAR) specific for CD138 and BCMA.

Dependencies are inferred from the claim text.

Facts

Application: 15/549,961Filed 9 Feb 2016
Priority: 9 Feb 2015
Published: 25 Jan 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

C07K 16/2896
Against receptors, cell surface antigens or cell surface determinants: against molecules with a "CD"-designation, not provided for elsewhere
A61K 35/12
Medicinal preparations containing materials or reaction products thereof with undetermined constitution: materials from mammals; Compositions…
A61K 40/11
Characterised by the cell type used: t-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer…
A61K 40/31
Characterised by the recombinant expression of specific molecules in the cells of the immune system: chimeric antigen receptors [CAR]

Family

Application62/114,045Us provisional application · filed 9 Feb 2015
Application62/121,862Us provisional application · filed 27 Feb 2015
US 10,647,778 B2Related patent
US 2018/0022815 A1This patent

From the US filing history. Foreign family members aren’t listed.

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