Equine immunoglobulin compositions and uses for treating filovirus-mediated diseases
AssigneesIntegrated Biotherapeutics, Inc., Auburn University
InventorsFrederick Wayne HOLTSBERG, Mohammad Javad AMAN, Paul H. WALZ, Stephanie R. OSTROWSKI
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Abstract
The disclosure provides a composition comprising immunoglobulin from an equine that has been hyper-immunized with a filovirus immunogen. The disclosure further provides methods of making such compositions and methods of using such compositions, e.g., for treating Ebola virus infection.
Claims56
A pharmaceutical composition comprising polyclonal immunoglobulin from an equine that has been hyper-immunized with a filovirus glycoprotein.
A method for preventing, treating, or managing a filovirus-mediated disease in a subject, comprising administering to a subject in need of treatment a polyclonal immunoglobulin from an equine that has been hyper-immunized with a filovirus glycoprotein.
Dependencies are inferred from the claim text.