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AssigneeThe Regents of the University of Michigan
InventorsJoseph BAZZILL, James Jaehyun MOON, Yuchen FAN, Preety SAHDEV
Estimating the term…
Provided herein are liposomal particles. In particular, provided herein are liposomal particles comprising molecules (e.g., antigens or drugs) and uses thereof (e.g., as a vaccine (e.g., intranasal vaccine) or drug delivery system). For example, in some embodiments, the present disclosure provides a composition comprising: a molecule encapsulated in a liposome comprising one or more cationic lipids and hyaluronic acid (HA). In some embodiments, the one or more lipids are DOTAP and/or DOPE. In some embodiments, the HA is thiolated. In some embodiments, the thiolated HA is conjugated to thiolated PEG.
A composition comprising:
(canceled)
A composition, comprising:
18-20. (canceled)
A method of delivering a molecule to a subject, comprising:
The method of claim 23, wherein said immune response induces immunity against a pathogen.
25-27. (canceled)
Dependencies are inferred from the claim text.