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US 2018/0021408 A1Published application
Fusion Proteins Containing Insulin-Like Growth Factor-1 and Epidermal Growth Factor and Variants Thereof and Uses Thereof
AssigneeIGF Oncology, LLC
InventorHugh McTavish
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Abstract
Fusion proteins comprising cytokines, particularly insulin-like growth factor-1 (IGF-1) and variants thereof, epidermal growth factor (EGF), and other ligands to the EGF receptor, are provided. The fusion proteins further comprise SEQ ID NO:1 or other segments having lysine, glutamic acid, or aspartic acid residues. Uses for the fusion proteins are also provided.
Claims6
A polypeptide comprising SEQ ID NO:1 or comprising residues 2-18 of SEQ ID NO:1;
- wherein the polypeptide has an N-terminus and SEQ ID NO:1 or residues 2-18 of SEQ ID NO:1 is at the N-terminus of the polypeptide.
2-6. (canceled)
10-30. (canceled)
Dependencies are inferred from the claim text.