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US 2018/0021369 A1Published application
Treatment of bone marrow edema (oedema) with polysulfated polysaccharides
AssigneeParadigm Health Sciences Pty Ltd
InventorPeter Ghosh
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Abstract
A method for the treatment of bone marrow edema in a mammal comprising administering an effective amount of a polysulfated polysaccharide including salts thereof, to a mammal in need of such treatment.
Claims9
A method for the treatment of bone marrow edema in a mammal, comprising:
- subjecting the mammal to a magnetic resonance imaging process,
- assessing one or more images generated from the magnetic resonance imaging process so as to detect the presence of a bone marrow edema,
- administering from about 1 mg/kg to about 2 mg/kg per dose of a polysulfated polysaccharide selected from the group consisting of pentosan polysulfate, a sodium salt of pentosan polysulfate (NaPPS), a magnesium salt of pentosan polysulfate (MgPPS), and a calcium salt of pentosan polysulfate (CaPPS) to the mammal if the bone marrow edema is detected in the mammal.
Dependencies are inferred from the claim text.