1-arylalkyl-4-acylaminopiperidine compounds
AssigneeArizona Board of Regents on Behalf of the University of Arizona
InventorsRuben S. Vardanyan, Victor J. Hruby
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Abstract
The present invention provides a compound of the formula: wherein ring Z is a 5-, 6- or 7-membered ring; R1 is C1-10 alkyl, C1-10 haloalkyl, optionally substituted aralkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heteroaralkyl; R2 is C1-10 alkylene; and Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula —C(═O)-X1, wherein X1 is —OR3 or —NR4R5, where each of R3, R4 and R5 is H or C1-10 alkyl. The present invention also provides a method for using compound of Formula I to treat a wide variety of clinical conditions.
Claims10
A compound of the formula:
- wherein
- ring Z is a 5-, 6- or 7-membered ring;
- R1 is C1-10 alkyl, C1-10 haloalkyl, optionally substituted aralkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heteroaralkyl;
- R2 is C1-10 alkylene;
- and
- Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula —C(═O)-X1, wherein X1 is —OR3 or —NR4R5, where each of R3, R4 and R5 is H or C1-10 alkyl.
Dependencies are inferred from the claim text.