Ketorolac for the treatment of cancer
AssigneeCipla Limited
InventorsGeena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
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Abstract
Methods of treating cancer, including PAR-4 implicated cancers or renal cell carcinoma, using ketorolac are disclosed herein. Ketorolac can be administered as a monotherapy or as part of a comprehensive treatment program, which can also include administration with other anti-cancer drugs, surgical treatments or exposure to ionizing radiation.
Claims19
A method for the treatment of renal cell carcinoma in a patient, the method comprising administering to said patient ketorolac, or a pharmaceutically acceptable salt or ester thereof, in an amount effective to treat renal cell carcinoma.
A method for treating cancer, comprising administering ketorolac, a pharmaceutically acceptable salt or ester thereof, to a patient in need thereof, in an amount effective to increase expression of prostate apoptosis response 4 (PAR-4).
A kit comprising ketorolac, a pharmaceutically acceptable salt or ester thereof, and at least one additional chemotherapeutic agent.
Dependencies are inferred from the claim text.