Intrinsic frequency analysis for left ventricle ejection fraction or stroke volume determination
AssigneeCalifornia Institute of Technology
InventorsNiema Pahlevan, Peyman Tavallali, Derek Rinderknecht, Morteza Gharib
Life of this patent
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Abstract
Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.
Claims13
1-11. (canceled)
A system for acquiring and analyzing a hemodynamic waveform, the system comprising:
- a light source to illuminate an area on a patient's skin;
- an optical sensor to determine a skin motion waveform at the area of the patient's skin illuminated by the light source;
- and
- a processor programmed to determine first and second intrinsic frequencies (IF) based on the measured skin motion waveform and to output a signal corresponding to at least one of left ventricle ejection fraction (LVEF) and stroke volume (SV) based on the determined first and second intrinsic frequencies.
A method for determining left ventricle ejection fraction (LVEF) and stroke volume (SV), the method comprising:
- illuminating an area on a patient's skin using a light source;
- determining a skin motion waveform at the area of the skin illuminated by the light source using an optical sensor;
- determining first and second intrinsic frequencies (IF) based on the measured skin motion waveform;
- and
- outputting a signal corresponding to at least one of left ventricle ejection fraction (LVEF) and stroke volume (SV).
Dependencies are inferred from the claim text.