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US 2017/0370836 A1Published application
Mobile/wearable devices incorporating lspr sensors
AssigneeLamdaGen Corporation
InventorsDaniele Gerion, Randolph Storer
Life of this patent
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Abstract
Sensor chips and devices that incorporate localized surface plasmon resonance (LSPR) sensors are described which are suitable for use in near-patient and point-of-care diagnostic testing. In some embodiments, LSPR sensors are integrated with microfabricated fluidics and other system components to create compact, portable bench-top or hand-held diagnostic testing systems. In some embodiments, all components are packaged in compact, portable wearable devices.
Claims46
A sensor chip comprising:
- a) one or more reaction wells, wherein each reaction well comprises a sensor surface capable of sustaining a localized surface plasmon resonance;
- b) a sample reservoir configured to contain a sample comprising an analyte;
- and
- c) one or more fluid conduits, wherein each fluid conduit connects the sample reservoir and one of the reaction wells;
- wherein the one or more sensor surfaces exhibit an analyte-induced change in optical property upon contact with the sample.
2 more elements
A device for detecting an analyte in a sample, the device comprising:
- a) a substrate comprising one or more localized surface plasmon resonance (LSPR) sensors, wherein analyte molecules are immobilized on a surface of the one or more LSPR sensors;
- and
- b) a cartridge, wherein the cartridge either partially or completely encloses the substrate, and wherein the surface(s) of the one or more LSPR sensors are accessible to addition of the sample.
Dependencies are inferred from the claim text.