Methods and systems to generate noncoding-coding gene co-expression networks

A method, comprising:

• receiving a plurality of RNA sequences in digital form in a memory;
• mapping some of the plurality of RNA sequences to coding genes based on a set of coding genes in a database;
• mapping another some of the plurality of RNA sequences to non-coding genes;
• determining variabilities of the coding genes and the non-coding genes;
• selecting the coding genes and non-coding genes that have variabilties above a threshold value;
• correlating with at least one processor the selected coding genes and the non-coding genes;
• and
• generating a co-expression network based, at least in part, on results of the correlating.

A system, comprising:

• at least one processor;
• a memory accessible to the at least one processor, the memory configured to store genetic sequences in digital form;
• a database accessible to the at least one processor;
• a display coupled to the at least one processor;
• and
• a non-transitory computer readable medium encoded with instructions that, when executed, cause the at least one processor to:
• receive the genetic sequences from the memory;
• map some of the genetic sequences to coding genes based on a set of coding genes in a database;
• map another some of the genetic sequences to non-coding genes;
• calculate variabilities of the coding genes and the non-coding genes;
• select the coding genes and non-coding genes that have variabilties above a threshold value;
• correlate with at least one processor the selected coding genes and the non-coding genes to determine a co-expression of the selected coding genes and non-coding genes;
• generate a co-expression network based, at least in part, on the co-expression;
• and
• provide the co-expression network to a user on the display.