Polymers for Inducing 3D Spheroid Formation of Biological Cells
AssigneeAkina, Inc.
InventorsJOHN SOLOMON GARNER, SARAH MICHELLE SKIDMORE, JUSTIN CHARLES HADAR, Burnsoo HAN, KINAM PARK
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Abstract
The present invention provides the use of selected thermogelling polymers for the purpose of growing tumor spheroids. The invention provides a thermogelling platform comprising a synthetic polymer which, when seeded with cancer cells, induces the cells to grow into a natural spheroidal pattern forming a tumor spheroid. After accomplishing this in about 3-10 days, the gel washes away, leaving behind the spheroids.
Claims48
A platform for inducing 3D spheroid formation of biological cells, comprising:
- a thermogelling polymer without amino acids.
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Dependencies are inferred from the claim text.