Back to results
US 2017/0360919 A1Published application
Nanoemulsion respiratory syncytial virus (rsv) subunit vaccine
AssigneeNanoBio Corporation
InventorsAli I. Fattom, Tarek Hamouda, Vira Bitko, James R. Baker, JR.
Life of this patent
Estimating the term…
Abstract
The present application relates to the field of immunology, in particular, a vaccine composition of respiratory syncytial virus (RSV) surface proteins, Fusion (F) and Glycoprotein (G) proteins subunit vaccine preferentially mixed with the immune cell targeting and enhancer, nanoemulsion to induce a protective immune response and avoid vaccine-induce disease enhancement.
Claims21
1-28. (canceled)
A method for inducing an enhanced immunity against diseases caused by respiratory syncytial viruses (RSV) comprising:
- (a) administering to a subject a first effective amount of a vaccine comprising:
- (i) at least one isolated RSV antigen or an antigenic fragment thereof;
- (ii) an immune-enhancing nanoemulsion or a dilution thereof, comprising droplets having an average size of about 1000 nm or less, an aqueous phase, at least one oil, at least one surfactant, and at least one organic solvent, wherein the isolated RSV antigen or antigenic fragment thereof is comprised within the nanoemulsion;
- and
- (b) administering to the subject a second boost amount of the same vaccine.
2 more elements
Dependencies are inferred from the claim text.