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US 2017/0326252 A1Published application
Nanoparticles for Delivery of Agents to Glioblastoma Tumors
AssigneeNanoforma Inc.
InventorAmy Shuen
Life of this patent
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Abstract
The present invention is, in general, directed to nanoparticles for the delivery of agents to glioblastoma tumors. More particularly, the present invention relates to nanoparticle conjugates that deliver and release agents to a glioblastoma tumor. The invention is also directed to methods of delivering agents to glioblastoma tumors.
Claims20
A method for delivering an agent to a glioblastoma tumor, comprising the steps of:
- providing a nanoparticle wherein the nanoparticle is a cylinder having a diameter of about 5 to 20 nanometers and a length of about 10 to 100 nanometers, wherein the agent is conjugated to the nanoparticle;
- administering the nanoparticle agent conjugate to a subject wherein the glioblastoma tumor is located in a brain of the subject, and delivering the nanoparticle agent conjugate to the glioblastoma tumor.
A method for delivering an agent to a glioblastoma tumor, comprising the steps of:
- providing a viral nanoparticle wherein the viral nanoparticle is a cylinder having a diameter of about 5 to 20 nanometers and a length of about 10 to 100 nanometers, wherein the nanoparticle comprises a cleavable linker that conjugates the agent to the nanoparticle, administering the viral nanoparticle agent conjugate to a subject who has the glioblastoma tumor;
- and cleaving the linker to release the agent, whereby the viral nanoparticle agent conjugate delivers the agent to the glioblastoma tumor.
Dependencies are inferred from the claim text.