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US 2017/0320914 A1Published application
Multivalent ligand-lipid constructs
OwnerNicolai Vladimirovich BOVIN, Stephen Micheal HENRY +3inventors
InventorsNicolai Vladimirovich BOVIN, Stephen Micheal HENRY, Elena KORCHAGINA, Igor Leonidovich RODIONOV, Alexander Borisovich TUZIKOV
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Abstract
Water dispersible, multivalent ligand-lipid constructs that spontaneously and stably incorporate into membranes are disclosed.
Claims13
1-14. (canceled)
A construct of the structure:
- where F is a ligand, L is a conjugated phosphatidylethanolamide and S is a tetraantennary spacer of the structure:
- where m is the integer 1, 2 or 3 and R is of the structure:
- where M is a monovalent cation or substituent, n is the integer 2, 3, 4, 5, 6 or 7, and * is the point of attachment of F or L.
Dependencies are inferred from the claim text.