Extracellular Matrix Sheet Structures

An implantable medical product, comprising:

• a bioremodelable pouch structure comprising an extracellular matrix (ECM) structure in sheet form, said ECM structure comprising acellular ECM from a decellularized mammalian tissue source, said decellularized mammalian tissue source being small intestine submucosa (SIS), urinary bladder submucosa, stomach submucosa, central nervous system tissue, epithelium of mesodermal origin, dermal extracellular matrix, subcutaneous extracellular matrix, gastrointestinal extracellular matrix, tissue surrounding growing bone, placental extracellular matrix, omentum extracellular matrix, cardiac extracellular matrix, kidney extracellular matrix, pancreas extracellular matrix, lung extracellular matrix, urinary basement membrane, liver basement membrane, and combinations thereof,
• said pouch structure comprising an internal region or cavity and an opening, wherein the pouch structure is configured to allow a composition or an object to be inserted into the internal region or cavity of the pouch;
• with the pouch structure formed from:
• (a) a single ECM sheet that is folded and that has edges which are joined together except for the edges that form the opening, or
• (b) two ECM sheets each having edges that are joined together except for the edges that form the opening;
• wherein the pouch structure effectively improves biological functions by promoting tissue regeneration, modulated healing of adjacent tissue or growth of new tissue when implanted in a body of a warm blooded mammal.