Lubricious medical device coating with low particulates
AssigneeSurModics, Inc.
InventorDavid E. Babcock
Life of this patent
Estimating the term…
Abstract
Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.
Claims20
A coating for a medical device comprising:
- a first layer comprising
- polyvinylpyrrolidone derivatized with a photoreactive group;
- and
- a first cross-linking agent comprising at least two photoreactive groups;
- and
- a second layer disposed on the first layer comprising
- polyvinylpyrrolidone derivatized with a photoreactive group;
- a second cross-linking agent comprising at least two photoreactive groups;
- wherein the coating releases less than 10,000 particles greater than 10 microns in size when exposed to an aqueous environment.
A coating for a medical device comprising:
- a first layer comprising
- polyvinylpyrrolidone derivatized with a photoreactive group;
- and
- a first cross-linking agent comprising at least two photoreactive groups;
- and
- a second layer disposed on the first layer comprising
- polyvinylpyrrolidone derivatized with a photoreactive group;
- a second cross-linking agent comprising at least two photoreactive groups;
- wherein the coating releases less than 1,592 particles greater than 10 microns in size per square centimeter of coating surface area when exposed to an aqueous environment.
Dependencies are inferred from the claim text.