Osteoimplant comprising an insoluble fibrous polymer
AssigneeWarsaw Orthopedic, Inc.
InventorsScott M. Vickers, Jeffrey L. Scifert, Mirian Gillissen, Didier Billy
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Abstract
Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.
Claims20
A method for making an osteoimplant, the method comprising:
- applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers;
- and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant.
An osteoimplant comprising entangled insoluble collagen fibers in an amount of from 75% to 100% by weight based on the total weight of the collagen in the osteoimplant.
A method of filling a bone cavity with a moldable osteoimplant, the method comprising:
- hydrating a lyophilized osteoimplant to obtain the moldable osteoimplant, the lyophilized osteoimplant comprising entangled insoluble collagen fibers in an amount of from 30% to 40% by weight based on the total weight of the osteoimplant;
- and filling the bone cavity with the moldable osteoimplant and allowing the osteoimplant to cure in place.
Dependencies are inferred from the claim text.