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US 2017/0304220 A1Published application
Xanthohumol in antiarrythmic applications
AssigneeUniversity of South Carolina
InventorsMartin Morad, Lars Cleemann, Juan Jose Arnaiz-Cot
Life of this patent
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Abstract
Methods for modulating Ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress Ca2+ signaling by suppressing spontaneous activity of the RyR2 receptor. Delivery of xanthohumol to a cardiocyte can be utilized in treatment of cardiac arrhythmia.
Claims16
A method for modulating Ca2+ signaling in a cardiac myocyte, the method comprising delivering a xanthohumol to the cardiac myocyte.
A composition comprising xanthohumerol, wherein the composition is configured for delivery to a cardiac myocyte for modulating Ca2+ signaling in the cardiac myocyte.
Dependencies are inferred from the claim text.