Personalized prosthesis and methods of use

A personalized prosthesis for implantation at a treatment site in a patient, said prosthesis comprising:

• a self-expanding mesh having a collapsed configuration and an expanded configuration, the collapsed configuration adapted to be delivered to the treatment site, and the expanded configuration is personalized to match and engage the treatment site,
• wherein the mesh in the expanded configuration has an outer surface that substantially matches a shape and size of the treatment site,
• wherein the self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough, and
• wherein the mesh is formed from a plurality of filaments twisted together to form a repeating circumferential pattern of three twists followed by two twists followed by two twists.