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US 2017/0290960 A1Published application
Drug delivery system and method of manufacturing thereof
AssigneeExogenesis Corporation
InventorsSean R. Kirkpatrick, Richard C. Svrluga, Stephen M. Blinn
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Abstract
A method of modifying the surface of a medical device to release a drug in a controlled way by providing a barrier layer on the surface of one or more drug coatings. The barrier layer consists of modified drug material converted to a barrier layer by irradiation by an accelerated neutral beam derived from an accelerated gas cluster ion beam. Also medical devices formed thereby.
Claims10
A method of modifying a surface of a medical device comprising the steps:
- a. depositing a first drug coating layer on at least a portion of the surface of the medical device;
- b. optionally depositing one or more additional drug coating layers on the first drug coating layer to form a plurality of drug coating layers;
- c. forming an accelerated Neutral Beam from a gas cluster ion beam from which charged particles have been separated;
- and
- d. irradiating a first exposed surface of at least one of the first drug coating layer or any additional drug coating layer with the accelerated Neutral Beam to form a barrier layer at the first exposed surface.
2 more elements
Dependencies are inferred from the claim text.