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US 2017/0287692 A1Published application
Combined Mass-to-Charge Ratio and Charge State Selection in Tandem Mass Spectrometry
AssigneeMicromass UK Limited
InventorsRobert Harold BATEMAN, Kevin GILES, Steven Derek PRINGLE, Jason Lee WILDGOOSE
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Abstract
A mass spectrometer is disclosed comprising an ion mobility spectrometer and an ion gate. A collision cell is arranged downstream of the ion gate. The operation of the ion mobility spectrometer and the ion gate are synchronized so that only ions having a particular mass to charge ration and a desired charge state are onwardly transmitted to the collision cell.
Claims20
A mass spectrometer comprising:
- a first mass to charge ratio filter or mass to charge ratio mass analyser arranged and adapted in a first mode of operation to transmit ions having a mass to charge ratio within a first range;
- an ion mobility spectrometer or separator;
- attenuation means for attenuating ions in a mode of operation;
- and
- a control device configured to control the operation of said attenuation means so that ions having mass to charge ratios within said first range but having one or more undesired first charge states are substantially attenuated.
2 more elements
A method of mass spectrometry using a mass spectrometer having an ion mobility spectrometer or separator, the method comprising:
- transmitting ions having mass to charge ratios within a first range through a first mass to charge ratio filter or mass to charge ratio mass analyser;
- and
- attenuating ions in a mode of operation with attenuation means by controlling the operation of said attenuation means so that the ions having mass to charge ratios within said first range but having one or more first undesired charge states are substantially attenuated.
Dependencies are inferred from the claim text.