Compositions and methods for diagnosis and prognosis of colorectal cancer
OwnerEva I-Wei AWinventor
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OwnerEva I-Wei AWinventor
Estimating the term…
Certain embodiments of the present invention provide methods and compositions related to the detection of colorectal cancer based upon the identification of biomarkers and combinations of biomarkers that indicate the present of colorectal cancer. One embodiment of the present invention provides a method for detecting colorectal cancer in a subject by obtaining a biological sample from the subject; detecting one or more biomarkers present in the sample; and comparing the concentrations and/or expression levels of the one or more biomarkers within the biological sample with the concentrations and/or expression levels of the one or more biomarkers in a normal control sample.
A method for detecting colorectal cancer in a subject comprising:
(canceled)
A kit for detecting colorectal cancer by comparing the presence or absence, or the amount or concentration, of one or more nucleic acid biomarkers in the biological sample with the presence or absence, or the amount or concentration, of one or more nucleic acid biomarkers in the normal control sample, comprising an mRNA extracting buffer, at least one reverse transcription enzyme, at least one pair of primers that have the nucleotide sequences encompassed coding for any one or more of the amino acid residues of the protein biomarkers listed in Table 1, and instructions for use.
A kit for detecting colorectal cancer by comparing the amount or concentration, of one or more biomarkers listed in table 1 in the biological sample with the amount or concentration, of one or more biomarkers in the normal control sample, comprising isotopically labeled peptides corresponding to peptides derived from one or more biomarkers in Table 1, an internal standard, a set of calibrators, and instruction for use.
Dependencies are inferred from the claim text.