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AssigneeYissum Research Development Company of the Hebrew University of Jerusalem Lt
InventorsOded Shoseyov, Lena MAGRISSO, Tzvi ZVIRIN
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The A method of modifying a glycosylation pattern of a polypeptide-of-interest in a plant or plant cell is provided. The method comprising expressing in a plant or plant cell transformed to express at least one glycosidase in a subcellular compartment, a nucleic acid sequence encoding the polypeptide-of-interest, such that the at least one glycosidase and the polypeptide-of-interest are co-localized to the subcellular compartment of the plant or plant cell, thereby modifying the glycosylation pattern of the polypeptide-of-interest in the plant or plant cell.
A method of producing a human polypeptide-of-interest, the method comprising expressing in a plant or plant cell:
A nucleic acid construct system comprising one or more nucleic acid constructs, said one or more nucleic acid constructs comprising a nucleic acid sequence encoding a human polypeptide of interest;
The nucleic acid construct system 14, wherein said cell wall binding peptide is a cellulose binding domain (CBD).
A transgenic plant or plant cell recombinantly expressing:
Dependencies are inferred from the claim text.