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US 2017/0283489 A1Published application
Chimeric Antigen Receptor Specific for SSEA4 Antigen
AssigneeMiltenyi Biotec GmbH
InventorsAndreas Bosio, Olaf Hardt, Andrea Aloia
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Abstract
The present invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain specific for SSEA4, a population of engineered cells expressing said CARs, and a pharmaceutical composition comprising said genetically modified cells expressing said CARs. The pharmaceutical composition may be for use of the treatment of cancer in a subject suffering from cancer, wherein at least a subpopulation of the cancerous cells of said cancer expresses SSEA4.
Claims14
A chimeric antigen receptor (CAR) comprising an antigen binding domain specific for SSEA4.
Dependencies are inferred from the claim text.