Aerosol inhalation device
AssigneeChiesi Farmaceutici S.p.A.
InventorsDiego Copelli, Andrea Casazza
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AssigneeChiesi Farmaceutici S.p.A.
InventorsDiego Copelli, Andrea Casazza
Estimating the term…
Actuators for a pressurised metered dose inhalers containing (a) a housing adapted to receive an aerosol canister containing a pressurised medicament formulation, (b) a nozzle block defining the receptacle for the aerosol canister valve stem, the expansion chamber or sump, the nozzle channel its external aperture, and (c) a mouthpiece portion comprising a central rounded opening of a defined width and distance from the nozzle aperture and a cylindrical recess, whose central axis is aligned with the central longitudinal axis of the mouthpiece portion and with the central longitudinal axis of the nozzle channel, provide a significant reduction in the non-respirable coarse fraction of the emitted aerosol medicament via inertial impaction and retention in the actuator rather than in the oro-pharynx, with consequent less associated side effects and oral candidiasis in the patient. In addition, the presence of the central rounded opening has minimal, negligible impact on the fine particle dose of the delivered aerosol particles.
An actuator for an aerosol inhalation device, comprising:
A tubular element, comprising:
A tubular element, comprising
Dependencies are inferred from the claim text.