Compositions and methods for wound healing
AssigneeWorcester Polytechnic Institute
InventorsGeorge PINS, Glenn GAUDETTE, Adam COLLETTE, William EDELMAN
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Abstract
The present invention relates, in part, to sutures which promote wound closure and/or healing. In particular, the present invention provides fibrin microthread sutures that mimic the mechanical behavior of a target tissue thereby reducing, for example, scarring, inflammation, and cell death at the ligature site, including monofilament sutures.
Claims26
A method for promoting wound closure and/or healing of a target tissue, comprising applying a suture that mimics the mechanical behavior of the target tissue to a subject in need thereof.
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11-24. (canceled)
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34-38. (canceled)
A method for promoting wound closure and/or healing of a target tissue, comprising applying a suture that mimics the stiffness behavior of the target tissue to a subject in need thereof, wherein the subject has not received a standard of care suture.
A method for promoting wound closure and/or healing of a target tissue, comprising applying a suture that mimics the stiffness behavior of the target tissue to a subject in need thereof, wherein the subject has not received an adjuvant therapy.
43-50. (canceled)
Dependencies are inferred from the claim text.