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US 2017/0281798 A1Published application
Synthetic Scaffolds for Metastasis Detection
AssigneeNorthwestern University
InventorsLonnie D. Shea, Samira M. Azarin, Robert M. Gower, Jacqueline Jeruss
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Abstract
Provided herein are synthetic scaffolds engineered to function as a pre-metastatic niche to detect metastasis. In particular, synthetic scaffolds described herein provide detection of the earliest events in metastasis, thereby enabling treatment of metastasis before the disease burden increases.
Claims15
A biomaterial implant comprising a polymer scaffold and one or more chemical and/or biological agents, wherein the biomaterial implant mimics a pre-metastatic niche, recruits circulating metastatic cells, and provides an environment for metastasis.
Dependencies are inferred from the claim text.