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US 2017/0281779 A1Published application
Method of treating patients non-responsive to palonosetron
AssigneeHeron Therapeutics, Inc.
InventorsJohn Barr, Erin O'Boyle, John B. Whelan
Life of this patent
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Abstract
A method for treating chemotherapy-induced nausea and vomiting in individuals undergoing chemotherapy and previously treated with, and whom failed to respond to, a 5-HT3 antagonist other than granisetron is described. Individuals who fail to respond to, for example, palonosetron, as evidenced by an inadequate prevention or attenuation of acute or delayed chemotherapy-induced nausea and vomiting, are treated with a semi-solid drug delivery vehicle that provides a sustained release of granisetron.
Claims26
A treatment method, comprising:
- administering to a patient receiving chemotherapy, a semi-solid drug delivery vehicle comprising a bioerodible polymer and granisetron, wherein the patient was previously treated with a 5-HT3 antagonist other than granisetron and failed to achieve a satisfactory prevention or reduction of acute or delayed chemotherapy-induced nausea and vomiting.
Dependencies are inferred from the claim text.