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US 2017/0281775 A1Published application
Modifications of solid 3-sn-phosphoglycerides
AssigneeBioMolecular Products, Inc.
InventorsDavid W. Yesair, Walter A. Shaw, Stephen W. Burgess, Robert Travis McKee
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Abstract
Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structure.
Claims10
A drug delivery composition comprising
- a lipid matrix and a pharmaceutically acceptable carrier, wherein at least part of the lipid matrix is in a phase other than a lamellar phase, hexagonal phase or inverse hexagonal phase, wherein the lipid matrix comprises lysophosphoglyceride, monoglyceride and fatty acid, and wherein the molar ratio of lysophosphoglyceride:the sum of monoglyceride and fatty acid in the lipid matrix is between 1:3 and 1:12.
-8. (canceled)
-20. (canceled)
Dependencies are inferred from the claim text.