Unitary combination of fsh and hcg
AssigneeFerring B.V.
InventorMarco Filicori
Life of this patent
Estimating the term…
Abstract
A novel ovulatory induction paradigm entails administration of hCG in combination with FSH during all stages of treatment, where the ratio of FSH to hCG is adjusted to optimize ovulatory stimulation and minimize complications. The use of compositions characterized by various FSH:hCG ratios enables the practitioner readily to tailor the treatment regimen and accommodate different therapeutic goals as well as individual patient responses to gonadotropin administration.
Claims22
-41. (canceled)
A pharmaceutical composition consisting of FSH and hCG in at least one pharmaceutically acceptable carrier, wherein the amount of FSH and hCG is selected from the group consisting of:
- 50 IU FSH and 100 IU hCG;
- 50 IU FSH and 200 IU hCG;
- 75 IU FSH and 25 IU hCG;
- 75 IU FSH and 50 IU hCG;
- 75 IU FSH and 75 IU hCG;
- 75 IU FSH and 100 IU hCG;
- 150 IU FSH and 10 IU hCG;
- 150 IU FSH and 25 IU hCG;
- 150 IU FSH and 50 IU hCG;
- 150 IU FSH and 75 IU hCG;
- and 150 IU FSH and 100 IU hCG.
The use, in the manufacture of a medicament for inducing ovulation, of a pharmaceutical composition consisting of FSH and hCG in at least one pharmaceutically acceptable carrier characterised by an amount of FSH and hCG that is selected from the group consisting of 50 IU FSH and 100 IU hCG;
- 50 IU FSH and 200 IU hCG;
- 75 IU FSH and 25 IU hCG;
- 75 IU FSH and 50 IU hCG;
- 75 IU FSH and 75 IU hCG;
- 75 IU FSH and 100 IU hCG;
- 150 IU FSH and 10 IU hCG;
- 150 IU FSH and 25 IU hCG;
- 150 IU FSH and 50 IU hCG;
- 150 IU FSH and 75 IU hCG;
- and 150 IU FSH and 100 IU hCG.
A product comprising one or more unit doses of an injectable formulation comprising a single pharmaceutical composition consisting of FSH and hCG in at least one pharmaceutically acceptable carrier, wherein the amount of FSH and hCG is selected from the group consisting of:
- 50 IU FSH and 100 IU hCG;
- 50 IU FSH and 200 IU hCG;
- 75 IU FSH and 25 IU hCG;
- 75 IU FSH and 50 IU hCG;
- 75 IU FSH and 75 IU hCG;
- 75 IU FSH and 100 IU hCG;
- 150 IU FSH and 10 IU hCG;
- 150 IU FSH and 25 IU hCG;
- 150 IU FSH and 50 IU hCG;
- 150 IU FSH and 75 IU hCG;
- and 150 IU FSH and 100 IU hCG.
Dependencies are inferred from the claim text.