Steroid hormone pharmaceutical composition
OwnerPhilip B. Inskeep, Peter H.R. Persicaner +4inventors
InventorsPHILIP B. INSKEEP, PETER H.R. PERSICANER, ANNETTE SHADIACK, THORSTEINN THORSTEINSSON, FREDERICK D. SANCILIO, JASON D. LEGASSIE
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Abstract
This disclosure provides a novel pharmaceutical composition for delivering steroid hormones, such as estradiol and progesterone, to a patient in need thereof.
Claims23
A pharmaceutical composition suitable for administering estradiol and progesterone to a subject in need thereof, the pharmaceutical composition comprising estradiol, progesterone, a lipophilic surfactant system comprising a first lipophilic surfactant and a second lipophilic surfactant, wherein the first and second lipophilic surfactants are different from each other, a hydrophilic surfactant system comprising first and second hydrophilic surfactants, and an optional terpene, wherein the pharmaceutical composition is completely or substantially free of fractionated vegetable oils.
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A pharmaceutical composition suitable for administering estradiol and progesterone to a subject in need thereof, the pharmaceutical composition comprising estradiol, progesterone, a lipophilic surfactant system comprising a first lipophilic surfactant and a second lipophilic surfactant, wherein the first and second lipophilic surfactants are different from each other, a hydrophilic surfactant system comprising first and second hydrophilic surfactants, and an optional terpene, wherein the pharmaceutical composition is completely or substantially free of fractionated vegetable oils, wherein both the estradiol and the progesterone are solubilized in the pharmaceutical composition, and wherein the pharmaceutical composition forms micelles.
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Dependencies are inferred from the claim text.