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US 2017/0281640 A1Published application
Pharmaceutical Compositions Containing a Muscle Relaxant and a Nonsteroidal Anti-Inflammatory Drugs (NSAID)
AssigneeProductos Maver, S.A. de C.V.
InventorsSilvia Romero Medina, Jorge Castro Luna, Karim Saul Solorza Camacho, Alejandro Maldonado Pérez
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Abstract
Provided herein is a stable pharmaceutical composition including meloxicam and methocarbamol in the form of granules, including a meglumine and sodium citrate complex to improve solubility. The pharmaceutical compositions are administered simultaneously and are kept separated in the pharmaceutical form that is administered. Also provided herein are methods for the treatment of disorders associated with muscle, skeletal muscle, and pain.
Claims7
An oral pharmaceutical composition comprising:
- i. a first granulated material containing meloxicam, meglumine, sodium citrate, a surfactant agent, a diluent agent, a disintegrant agent, an agglutinant agent, and a moisturizing solution with a mixture of a pharmaceutically acceptable alcohol and water;
- ii. a second granulated material containing methocarbamol or its pharmaceutically acceptable salts, an agglutinant agent, and a moisturizing solution with a mixture of ethanol and water;
- and
- iii. optionally, a lubricant agent,
- wherein the proportion of sodium citrate to meglumine is in the range of 8:1 to 4:1.
2 more elements
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Dependencies are inferred from the claim text.