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US 2017/0281638 A1Published application
A salt of cephalosporin derivative, its crystalline solid and a method of manufacturing thereof
AssigneeShionogi & Co., Ltd.
InventorsFumihiko MATSUBARA, Takanori KURITA, Daiki NAGAMATSU
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Abstract
The present invention provides an acid addition salt or a sodium salt of a compound represented by the formula (IA): or their hydrate or a stable crystalline solid thereof. The salt or the crystalline solid is extremely useful as an active ingredient for the production of a pharmaceutical product.
Claims28
An acid addition salt or a sodium salt of a compound represented by the formula (IA):
- or a hydrate thereof;
- provided that the acid is 1) an acid having a substituted or unsubstituted benzenesulfonic acid group or 2) a mixed acid comprising an acid having a substituted or unsubstituted benzenesulfonic acid group and an inorganic acid.
A pharmaceutical composition containing the compound (IA), its pharmaceutically acceptable salt, or a hydrate thereof, and further sodium p-toluenesulfonate and/or sodium sulfate.
Dependencies are inferred from the claim text.