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US 2017/0281620 A1Published application
Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity
AssigneeParion Sciences, Inc.
InventorMichael Ross JOHNSON
Life of this patent
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Abstract
A very stable, selective and renally safe sodium channel blocker represented by the formula: The invention also includes a variety of compositions, combinations and methods of treatment using this inventive sodium channel blocker.
Claims5
1-23. (canceled)
A method of preparing a hydrochloric acid addition salt of a compound represented by formula (I):
- comprising:
- treating a compound represented by formula (14):
- with an effective amount of trifluoroacetic acid followed by azeotropimg with aqueous HCl.
Dependencies are inferred from the claim text.